Hybrid peptide BIO effectively reduces fine wrinkle through stimulation of the collagen production in the fibroblast cells, collagen-XVII/laminin-5/integrin α6 production in the keratinocyte, adipogenesis in the pre-adipocyte, and myogenesis in the myocytes.
Step1 : Collagen type-1
Hybrid Peptide BIO increases expression of
collagen type1 in 3D artificial skin.
Hybrid Peptide BIO prevents keratinocyte-mediated
reduction of collagen synthesis
Step2 : Cell-to-cell communication
Hybrid Peptide BIO increases expression of collagen XVII, laminin-5, and integrin α-6 in keratinocyte cells
Step3 : Adipogenesis
Hybrid Peptide BIO enhances formation of lipid
droplet in activated pre-adipocyte cells
Final effect : Wrinkle reduction
Use of Hybrid Peptide BIO contained product can
reduce fine wrinkle